Government Owned Invention Available for License: Quantitative Particle Identification (QPID) Digital Autoradiography System

Document Headings Document headings vary by document type but may contain the following: the agency or agencies that issued and signed a document the number of the CFR title and the number of each part the document amends, proposes to amend, or is directly related to the agency docket number / agency internal file number the RIN which identifies each regulatory action listed in the Unified Agenda of Federal Regulatory and Deregulatory Actions See the Document Drafting Handbook for more details. Department of Health and Human Services National Institutes of Health AGENCY: National Institutes of Health, HHS. ACTION: Notice. SUMMARY: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a QPID digital autoradiography system with particle identification capabilities. FOR FURTHER INFORMATION CONTACT: Inquiries related to this license opportunity should be directed to: Eric Cheng, Ph.D., Technology Transfer Manager, NCI, Technology Transfer Center, Email: eric.cheng2@nih.gov or Phone: 240-276-5978. SUPPLEMENTARY INFORMATION: Autoradiography is a photographic process that exposes a medium, sensitive to radiation, to a sample emitting radiation. The current state of the art involves exposing a thin slice of tissue to an ionization-sensitive film for several hours or days and then scanning the film into an autoradiography image. This image is created using the sum of the ionizations from all the decays that occurred during the time of exposure on the ionization-sensitive medium. Imaging quality of these samples can be improved by collecting information from each individual decay to enhance the autoradiographic measurement. Researchers at NCI developed a QPID digital autoradiography system to measure the energy deposition from charged particles for each individual radioactive decay. The QPID leverages the ionizing radiation detection features of the Timepix3 detector to generate autoradiograph images in units of dose per unit time and…